中文名称：氮杂二苯并环辛炔胺，二苯基环辛炔-氨基
中文别名：氨基丙酰氮杂二苯并环辛炔
英文名称：Azadibenzocylooctyne-amine
英文别名：Dibenzocyclooctyne-amine;DBCO-NH2;DBCO-amine;ADIBO-AMINE;
CAS号:
分子式：C18H16N2O
分子量:
精确质量:
PSA:
LogP:3.04710
名称：DBCO-Amine MWnbsp; CAS
英文简介：
A carboxyl-reactive building block containing DBCO moiety and a terminal primary amine group.
DBCO-Amine is a simple DBCO-containing reagent possessing a terminal primary amines group (–NH2) that reacts with carboxyl groups in the presence of activators (e.g. EDC, or DCC) or with activated esters (e.g. NHS esters) forming stable amide bonds. A short spacer arm adds minimal mass to modified moleculesdaltons).
名称：DBCO-PEG4-Amine MW:523.62
英文简介：
A carbonyl-reactive building block with enhanced solubility in aqueous media.
DBCO-PEG4-Amine is a polyethylene glycol-containing reagent with terminal primary amines (–NH2) that reacts with carboxyl groups in the presence of activators (e.g. EDC, or DCC) or with activated esters (e.g. NHS esters) forming stable amide bonds. A hydrophilic spacer arm enhances solubility in aqueous buffers.
名称：DBCO-NHS Ester MW：402.40
英文介绍：
DBCO-NHS Ester reacts with primary amines
This product is not recommended for labeling of proteins or any other biopolymers in aqueous buffers due to poor aqueous solubility.
名称: DBCO-C6-NHS Ester MW:430.45
英文介绍：
An activated ester with extended 6-carbon atom long spacer.
DBCO-NHS Ester reacts with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form covalent bonds. Extended 6-carbon spacer arm is beneficial for some application. This reagent has limited shelf life; however, corresponding acid and its derivatives are found to be stable over long period of time. DBCO-Sulfo-NHS-Ester, a water-soluble version of this product is also available for labeling experiments where the presence of organic solvents is highly undesirable.
名称：DBCO-PEG5-NHS Ester MW:693.74
英文简介：
An amine-reactive labeling reagent with enhanced water stability and solubility.
DBCO-PEG5-NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the labeled molecule, thus reducing aggregation of labeled proteins stored in solution. The PEG spacer arm provides a long and flexible connection that minimizes steric hindrance involved with ligation to complementary azide-containing molecules.
名称：DBCO-PEG4-NHS Ester MW:649.68
英文简介：
An amine-reactive labeling reagent with enhanced water solubility provided by a PEG4 spacer.
DBCO-PEG4-NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the labeled molecule, thus reducing aggregation of labeled proteins stored in solution. The PEG spacer arm provides a long and flexible connection that minimizes steric hindrance involved with ligation to complementary azide-containing molecules.
名称：DBCO-Acid MW:305.11
英文简介：
DBCO-Acid is an amine reactive, non-activated cyclooctyne building block.
The use of strained cyclooctynes instead of terminal alkynes allows for overcoming a major drawback of copper-catalyzed azide-alkyne cycloaddition (CuAAC) - the need for the toxic copper catalyst. The ring strain in cyclooctynes, such as DBCO-Acid makes them highly reactive in the cycloaddition reaction. This reaction was termed as the strain-promoted alkyne-azide cycloaddition (SPAAC) or copper-free click reaction and has been widely used for bioconjugation and for labeling living cells and living animals.
