中文名称:奥拉帕尼
中文同义词:奥拉帕尼,PARP抑制剂;4-[4-氟-3-(哌嗪-1-环丙基羰基)苄基]-2H-酞嗪-1-酮;4-[3-[4-(环丙烷羰基)哌嗪-1-羰基]-4-氟苄基]酞嗪-1(2H)-酮;奥拉帕尼1G;奥拉帕利;1-(环丙甲酰基)-4-[5-[(3,4-二氢-4-氧代-1-酞嗪基)甲基]-2-氟苯甲酰]哌嗪;奥拉帕尼;
英文名称:Olaparib
英文同义词:1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]piperazin;OlaparidAZD2281;4-(3-(4-(Cyclopropanecarbonyl)piperazi ne-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one;4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]Methyl]-1(2H)-phthalazinone;KU59436;AZD2281(olaparib)/AZD-2281;AZD2281(olaparib);4-(3-(1-(cyclopropanecarbonyl)piperazine-4-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
CAS号:763113-22-0
分子式:C24H23FN4O3
分子量:434.46
EINECS号:642-941-5
密度1.43
储存条件-20°C
溶解度SolubleinDMSO(upto33mg/ml)orinEthanol(up to1.7mg/ml)
酸度系数(pKa)12.07±0.40(Predicted)
形态solid
颜色Off-white
